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It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)
A balanced diet should provide most individuals with adequate vitamin B12 levels, and supplementation in the form of oral supplements or patches may be sufficient for those with specific dietary limitations or absorption issues
Vitamin B 12 deficiency resulting from inadequate dietary intake is the easiest to treat
Theyre also approved for helping to treat serious wounds from trauma or burns
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